Valerolactone from Levulinate in Pseudomonas putida KT2440
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چکیده
منابع مشابه
Integrated bioprocessing for the pH-dependent production of 4-valerolactone from levulinate in Pseudomonas putida KT2440.
Enzymes are powerful biocatalysts capable of performing specific chemical transformations under mild conditions, yet as catalysts they remain subject to the laws of thermodynamics, namely, that they cannot catalyze chemical reactions beyond equilibrium. Here we report the phenomenon and application of using extracytosolic enzymes and medium conditions, such as pH, to catalyze metabolic pathways...
متن کاملIntegrated Bioprocessing for the pH-Dependent Production of 4- Levulinate in Pseudomonas putida KT2440 Citation
The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Abstract 24 Enzymes are powerful biocatalysts capable of performing specific chemical 25 transformations under mild conditions. Yet as catalysts they remain subject to the laws 26 of thermodynamics, namely that they cannot catalyze chemical reactions beyond 27 equilibrium. Here...
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Pseudomonas putida KT2440 is frequently used in biotechnical research and applications due to its metabolic versatility and organic solvent resistance. A major drawback for a broad application is the inability of the bacterium to survive and grow under anoxic conditions, which prohibits the production of oxygen-sensitive proteins and metabolites. To develop a P. putida strain, which is able to ...
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Bacterial toxin/antitoxin (TA) systems have received increasing attention due to their prevalence, diverse structures, and important physiological functions. In this study, we identified and characterized a type II TA system in a soil bacterium Pseudomonas putida KT2440. This TA system belongs to the MqsR/MqsA family. We found that PP_4205 (MqsR) greatly inhibits cell growth in P. putida KT2440...
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